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Mesenchymal stem cell transformation and sarcoma genesis

MSCs are hypothesized to potentially give rise to sarcomas after transformation and therefore serve as a good model to study sarcomagenesis. Both spontaneous and induced transformation of MSCs have been reported, however, spontaneous transformation has only been convincingly shown in mouse MSCs whil...

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Detalles Bibliográficos
Autores principales: Xiao, Wei, Mohseny, Alexander B, Hogendoorn, Pancras C W, Cleton-Jansen, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724575/
https://www.ncbi.nlm.nih.gov/pubmed/23880362
http://dx.doi.org/10.1186/2045-3329-3-10