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Identification of the likely translational start of Mycobacterium tuberculosis GyrB

BACKGROUND: Bacterial DNA gyrase is a validated target for antibacterial chemotherapy. It consists of two subunits, GyrA and GyrB, which form an A(2)B(2) complex in the active enzyme. Sequence alignment of Mycobacterium tuberculosis GyrB with other bacterial GyrBs predicts the presence of 40 potenti...

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Detalles Bibliográficos
Autores principales: Karkare, Shantanu, Brown, Amanda C, Parish, Tanya, Maxwell, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724585/
https://www.ncbi.nlm.nih.gov/pubmed/23856181
http://dx.doi.org/10.1186/1756-0500-6-274