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Mutations of Residues 249 and 256 in VP2 Are Involved in the Replication and Virulence of Infectious Bursal Disease Virus
Infectious bursal disease virus (IBDV) is a pathogen of worldwide significance to the poultry industry. Although the P(DE) and P(FG) domains of the capsid protein VP2 contribute significantly to virulence and fitness, the detailed molecular basis for the pathogenicity of IBDV is still not fully unde...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724781/ https://www.ncbi.nlm.nih.gov/pubmed/23923037 http://dx.doi.org/10.1371/journal.pone.0070982 |