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Lysine-Specific Demethylase 1 (LSD1/KDM1A) Contributes to Colorectal Tumorigenesis via Activation of the Wnt/Β-Catenin Pathway by Down-Regulating Dickkopf-1 (DKK1)

We collected paired samples of tumor and adjacent normal colorectal tissues from 22 patients with colorectal carcinoma to compare the differences in the expression of lysine specific demethylase 1 (LSD1) in these two tissues. The results showed that in 19 paired samples (86.4%), LSD1 is more highly...

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Detalles Bibliográficos
Autores principales: Huang, Zebin, Li, Shangze, Song, Wei, Li, Xin, Li, Qinshan, Zhang, Zeyan, Han, Yongqing, Zhang, Xiaodong, Miao, Shiying, Du, Runlei, Wang, Linfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724785/
https://www.ncbi.nlm.nih.gov/pubmed/23922913
http://dx.doi.org/10.1371/journal.pone.0070077