The Natural Pesticide Dihydrorotenone Induces Human Plasma Cell Apoptosis by Triggering Endoplasmic Reticulum Stress and Activating p38 Signaling Pathway

Dihydrorotenone (DHR) is a natural pesticide widely used in farming industry, such as organic produces. DHR is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome, however, it is not known whether DHR is toxic to other systems. In the present study, we evaluated the cytotoxic...

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Detalles Bibliográficos
Autores principales: Zhang, Jieyu, Tang, Juan, Cao, Biyin, Zhang, Zubin, Li, Jie, Schimmer, Aaron D., He, Sudan, Mao, Xinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724796/
https://www.ncbi.nlm.nih.gov/pubmed/23922854
http://dx.doi.org/10.1371/journal.pone.0069911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724796/
https://www.ncbi.nlm.nih.gov/pubmed/23922854
http://dx.doi.org/10.1371/journal.pone.0069911

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