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STAT3 Signaling Induces the Differentiation of Human ICOS(+) CD4 T Cells Helping B lymphocytes
The generation of high-affinity antibodies and the development of B cell memory are dependent on the help provided by CD4 T cells. Mouse studies indicate that STAT3 signaling in CD4 T cells promotes the acquisition of the B cell help function. However, the role of STAT3 in humans has been controvers...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724802/ https://www.ncbi.nlm.nih.gov/pubmed/23923047 http://dx.doi.org/10.1371/journal.pone.0071029 |