Cargando…

SIRT1 is a Direct Coactivator of Thyroid Hormone Receptor β1 with Gene-Specific Actions

Sirtuin 1 (SIRT1) NAD(+)-dependent deacetylase regulates energy metabolism by modulating expression of genes involved in gluconeogenesis and other liver fasting responses. While many effects of SIRT1 on gene expression are mediated by deacetylation and activation of peroxisome proliferator activated...

Descripción completa

Detalles Bibliográficos
Autores principales: Suh, Ji Ho, Sieglaff, Douglas H., Zhang, Aijun, Xia, Xuefeng, Cvoro, Aleksandra, Winnier, Glenn E., Webb, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724829/
https://www.ncbi.nlm.nih.gov/pubmed/23922917
http://dx.doi.org/10.1371/journal.pone.0070097