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Regulatory CD4(+)Foxp3(+) T Cells Control the Severity of Anaphylaxis

OBJECTIVE: Anaphylaxis is a life-threatening outcome of immediate-type hypersensitivity to allergen, consecutive to mast cell degranulation by allergen-specific IgE. Regulatory T cells (Treg) can control allergic sensitization and mast cell degranulation, yet their clinical benefit on anaphylactic s...

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Detalles Bibliográficos
Autores principales: Kanjarawi, Reem, Dy, Michel, Bardel, Emilie, Sparwasser, Tim, Dubois, Bertrand, Mecheri, Salah, Kaiserlian, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724852/
https://www.ncbi.nlm.nih.gov/pubmed/23922690
http://dx.doi.org/10.1371/journal.pone.0069183