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Targeting the Giant Cell Tumor Stromal Cell: Functional Characterization and a Novel Therapeutic Strategy

Giant cell tumor of bone (GCTB) is a benign, locally destructive neoplasm, with tumors comprised of mesenchymal fibroblast-like stromal cells; monocytic, mononuclear cells of myeloid lineage; and the characteristic osteoclast-like, multinucleated giant cells. Hampering the study of the complex inter...

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Detalles Bibliográficos
Autores principales: Steensma, Matthew R., Tyler, Wakenda K., Shaber, Allison G., Goldring, Steven R., Ross, F. Patrick, Williams, Bart O., Healey, John H., Purdue, P. Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724882/
https://www.ncbi.nlm.nih.gov/pubmed/23922683
http://dx.doi.org/10.1371/journal.pone.0069101