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Targeting the Giant Cell Tumor Stromal Cell: Functional Characterization and a Novel Therapeutic Strategy
Giant cell tumor of bone (GCTB) is a benign, locally destructive neoplasm, with tumors comprised of mesenchymal fibroblast-like stromal cells; monocytic, mononuclear cells of myeloid lineage; and the characteristic osteoclast-like, multinucleated giant cells. Hampering the study of the complex inter...
Autores principales: | Steensma, Matthew R., Tyler, Wakenda K., Shaber, Allison G., Goldring, Steven R., Ross, F. Patrick, Williams, Bart O., Healey, John H., Purdue, P. Edward |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724882/ https://www.ncbi.nlm.nih.gov/pubmed/23922683 http://dx.doi.org/10.1371/journal.pone.0069101 |
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