PrP(ST), a Soluble, Protease Resistant and Truncated PrP Form Features in the Pathogenesis of a Genetic Prion Disease

While the conversion of PrP(C) into PrP(Sc) in the transmissible form of prion disease requires a preexisting PrP(Sc) seed, in genetic prion disease accumulation of disease related PrP could be associated with biochemical and metabolic modifications resulting from the designated PrP mutation. To inv...

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Detalles Bibliográficos
Autores principales: Friedman-Levi, Yael, Mizrahi, Michal, Frid, Kati, Binyamin, Orli, Gabizon, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724911/
https://www.ncbi.nlm.nih.gov/pubmed/23922744
http://dx.doi.org/10.1371/journal.pone.0069583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724911/
https://www.ncbi.nlm.nih.gov/pubmed/23922744
http://dx.doi.org/10.1371/journal.pone.0069583

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