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Myeloid-Derived Suppressor Cells Modulate Immune Responses Independently of NADPH Oxidase in the Ovarian Tumor Microenvironment in Mice

The phagocyte NADPH oxidase generates superoxide anion and downstream reactive oxidant intermediates in response to infectious threat, and is a critical mediator of antimicrobial host defense and inflammatory responses. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immat...

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Detalles Bibliográficos
Autores principales: Godoy, Heidi E., Khan, A. Nazmul H., Vethanayagam, R. Robert, Grimm, Melissa J., Singel, Kelly L., Kolomeyevskaya, Nonna, Sexton, Kevin J., Parameswaran, Anupama, Abrams, Scott I., Odunsi, Kunle, Segal, Brahm H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724928/
https://www.ncbi.nlm.nih.gov/pubmed/23922763
http://dx.doi.org/10.1371/journal.pone.0069631