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Myeloid-Derived Suppressor Cells Modulate Immune Responses Independently of NADPH Oxidase in the Ovarian Tumor Microenvironment in Mice
The phagocyte NADPH oxidase generates superoxide anion and downstream reactive oxidant intermediates in response to infectious threat, and is a critical mediator of antimicrobial host defense and inflammatory responses. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immat...
Autores principales: | Godoy, Heidi E., Khan, A. Nazmul H., Vethanayagam, R. Robert, Grimm, Melissa J., Singel, Kelly L., Kolomeyevskaya, Nonna, Sexton, Kevin J., Parameswaran, Anupama, Abrams, Scott I., Odunsi, Kunle, Segal, Brahm H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724928/ https://www.ncbi.nlm.nih.gov/pubmed/23922763 http://dx.doi.org/10.1371/journal.pone.0069631 |
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