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Mechanisms of HIV Entry into the CNS: Increased Sensitivity of HIV Infected CD14(+)CD16(+) Monocytes to CCL2 and Key Roles of CCR2, JAM-A, and ALCAM in Diapedesis

As HIV infected individuals live longer, the prevalence of HIV associated neurocognitive disorders is increasing, despite successful antiretroviral therapy. CD14(+)CD16(+) monocytes are critical to the neuropathogenesis of HIV as they promote viral seeding of the brain and establish neuroinflammatio...

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Detalles Bibliográficos
Autores principales: Williams, Dionna W., Calderon, Tina M., Lopez, Lillie, Carvallo-Torres, Loreto, Gaskill, Peter J., Eugenin, Eliseo A., Morgello, Susan, Berman, Joan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724935/
https://www.ncbi.nlm.nih.gov/pubmed/23922698
http://dx.doi.org/10.1371/journal.pone.0069270