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Ankyrin repeat and suppressor of cytokine signaling box containing protein-10 is associated with ubiquitin-mediated degradation pathways in trabecular meshwork cells

PURPOSE: Ankyrin repeat and suppressor of cytokine signaling (SOCS) box containing protein-10 (ASB10) was recently identified as a gene that causes primary open-angle glaucoma. Here, we investigated endogenous ASB10 protein expression in human trabecular meshwork (HTM) cells to provide the first clu...

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Detalles Bibliográficos
Autores principales: Keller, Kate E., Yang, Yong-feng, Sun, Ying Ying, Sykes, Renee, Acott, Ted S., Wirtz, Mary K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724959/
https://www.ncbi.nlm.nih.gov/pubmed/23901248