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Quercetin suppresses inflammation by reducing ERK1/2 phosphorylation and NF kappa B activation in Leptin-induced Human Umbilical Vein Endothelial Cells (HUVECs)

BACKGROUND: High concentrations of plasma leptin and the release of pro-inflammatory cytokines in leptin-resistance in obesity have been reported to trigger endothelial dysfunction. The objective of this study was to elucidate the role of quercetin in modulating leptin-induced inflammation as assess...

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Detalles Bibliográficos
Autores principales: Indra, Mochamad Rasjad, Karyono, Satuman, Ratnawati, Retty, Malik, Safarina G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725156/
https://www.ncbi.nlm.nih.gov/pubmed/23856194
http://dx.doi.org/10.1186/1756-0500-6-275