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Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells
BACKGROUND: Activation of receptors for growth factors on lung epithelial cells is essential for transformation into tumor cells, supporting their viability and proliferation. In most lung cancer patients, EGFR is constitutively activated without evidence of mutation. Defining mechanisms for constit...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725175/ https://www.ncbi.nlm.nih.gov/pubmed/23866081 http://dx.doi.org/10.1186/1476-4598-12-76 |