Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells

BACKGROUND: Activation of receptors for growth factors on lung epithelial cells is essential for transformation into tumor cells, supporting their viability and proliferation. In most lung cancer patients, EGFR is constitutively activated without evidence of mutation. Defining mechanisms for constit...

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Detalles Bibliográficos
Autores principales: Sutton, Parnetta, Borgia, Jeffrey A, Bonomi, Philip, Plate, Janet MD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725175/
https://www.ncbi.nlm.nih.gov/pubmed/23866081
http://dx.doi.org/10.1186/1476-4598-12-76

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