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GluN2B in corticostriatal circuits governs choice learning and choice shifting

A choice that reliably produces a preferred outcome can be automated to liberate cognitive resources for other tasks. Should an outcome become less desirable, behavior must adapt in parallel or become perseverative. Corticostriatal systems are known to mediate choice learning and flexibility, but th...

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Detalles Bibliográficos
Autores principales: Brigman, Jonathan L., Daut, Rachel, Wright, Tara, Gunduz-Cinar, Ozge, Graybeal, Carolyn, Davis, Margaret I., Jiang, Zhihong, Saksida, Lisa, Jinde, Seiichiro, Pease, Matthew, Bussey, Timothy J., Lovinger, David M., Nakazawa, Kazu, Holmes, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725191/
https://www.ncbi.nlm.nih.gov/pubmed/23831965
http://dx.doi.org/10.1038/nn.3457