Unusual architecture of the p7 channel from hepatitis C virus

The Hepatitis C virus (HCV) has developed a small membrane protein, p7, which remarkably can self-assemble into a large channel complex that selectively conducts cations(1-4). We are curious as to what structural solution has the viroporin adopted to afford selective cation conduction because p7 has...

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Detalles Bibliográficos
Autores principales: OuYang, Bo, Xie, Shiqi, Berardi, Marcelo J., Zhao, Xinhao, Dev, Jyoti, Yu, Wenjing, Sun, Bing, Chou, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725310/
https://www.ncbi.nlm.nih.gov/pubmed/23739335
http://dx.doi.org/10.1038/nature12283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725310/
https://www.ncbi.nlm.nih.gov/pubmed/23739335
http://dx.doi.org/10.1038/nature12283

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