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Unusual architecture of the p7 channel from hepatitis C virus

The Hepatitis C virus (HCV) has developed a small membrane protein, p7, which remarkably can self-assemble into a large channel complex that selectively conducts cations(1-4). We are curious as to what structural solution has the viroporin adopted to afford selective cation conduction because p7 has...

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Detalles Bibliográficos
Autores principales:	OuYang, Bo, Xie, Shiqi, Berardi, Marcelo J., Zhao, Xinhao, Dev, Jyoti, Yu, Wenjing, Sun, Bing, Chou, James J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725310/ https://www.ncbi.nlm.nih.gov/pubmed/23739335 http://dx.doi.org/10.1038/nature12283

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