The Phosphatase PP4c Controls Spindle Orientation to Maintain Proliferative Symmetric Divisions in the Developing Neocortex

In the developing neocortex, progenitor cells expand through symmetric division before they generate cortical neurons through multiple rounds of asymmetric cell division. Here, we show that the orientation of the mitotic spindle plays a crucial role in regulating the transition between those two div...

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Detalles Bibliográficos
Autores principales: Xie, Yunli, Jüschke, Christoph, Esk, Christopher, Hirotsune, Shinji, Knoblich, Juergen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725415/
https://www.ncbi.nlm.nih.gov/pubmed/23830831
http://dx.doi.org/10.1016/j.neuron.2013.05.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725415/
https://www.ncbi.nlm.nih.gov/pubmed/23830831
http://dx.doi.org/10.1016/j.neuron.2013.05.027

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