Structural insights into the activation of MST3 by MO25

The MO25 scaffolding protein operates as critical regulator of a number of STE20 family protein kinases (e.g. MST and SPAK isoforms) as well as pseudokinases (e.g. STRAD isoforms that play a critical role in activating the LKB1 tumour suppressor). To better understand how MO25 interacts and stimulat...

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Detalles Bibliográficos
Autores principales: Mehellou, Youcef, Alessi, Dario R., Macartney, Thomas J., Szklarz, Marta, Knapp, Stefan, Elkins, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725419/
https://www.ncbi.nlm.nih.gov/pubmed/23296203
http://dx.doi.org/10.1016/j.bbrc.2012.12.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725419/
https://www.ncbi.nlm.nih.gov/pubmed/23296203
http://dx.doi.org/10.1016/j.bbrc.2012.12.113

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