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A role for thioredoxin-interacting protein (Txnip) in cellular creatine homeostasis
Creatine is important for energy metabolism, yet excitable cells such as cardiomyocytes do not synthesize creatine and rely on uptake via a specific membrane creatine transporter (CrT; SLC6A8). This process is tightly controlled with downregulation of CrT upon continued exposure to high creatine via...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725544/ https://www.ncbi.nlm.nih.gov/pubmed/23715727 http://dx.doi.org/10.1152/ajpendo.00637.2012 |