Both ERK/MAPK and TGF-Beta/Smad Signaling Pathways Play a Role in the Kidney Fibrosis of Diabetic Mice Accelerated by Blood Glucose Fluctuation

Background. The notion that diabetic nephropathy is the leading cause of renal fibrosis prompted us to investigate the effects of blood glucose fluctuation (BGF) under high glucose condition on kidney in the mice. Methods. The diabetic and BGF animal models were established in this study. Immunohist...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaoyun, Gao, Wenke, Dang, Yongyan, Liu, Xia, Li, Yujuan, Peng, Xu, Ye, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725803/
https://www.ncbi.nlm.nih.gov/pubmed/23936866
http://dx.doi.org/10.1155/2013/463740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725803/
https://www.ncbi.nlm.nih.gov/pubmed/23936866
http://dx.doi.org/10.1155/2013/463740

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