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Both ERK/MAPK and TGF-Beta/Smad Signaling Pathways Play a Role in the Kidney Fibrosis of Diabetic Mice Accelerated by Blood Glucose Fluctuation
Background. The notion that diabetic nephropathy is the leading cause of renal fibrosis prompted us to investigate the effects of blood glucose fluctuation (BGF) under high glucose condition on kidney in the mice. Methods. The diabetic and BGF animal models were established in this study. Immunohist...
Autores principales: | Cheng, Xiaoyun, Gao, Wenke, Dang, Yongyan, Liu, Xia, Li, Yujuan, Peng, Xu, Ye, Xiyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725803/ https://www.ncbi.nlm.nih.gov/pubmed/23936866 http://dx.doi.org/10.1155/2013/463740 |
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