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Blockade of bovine PD-1 increases T cell function and inhibits bovine leukemia virus expression in B cells in vitro

Programmed death-1 (PD-1) is a known immunoinhibitory receptor that contributes to immune evasion of various tumor cells and pathogens causing chronic infection, such as bovine leukemia virus (BLV) infection. First, in this study, to establish a method for the expression and functional analysis of b...

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Detalles Bibliográficos
Autores principales: Ikebuchi, Ryoyo, Konnai, Satoru, Okagawa, Tomohiro, Yokoyama, Kazumasa, Nakajima, Chie, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726328/
https://www.ncbi.nlm.nih.gov/pubmed/23876077
http://dx.doi.org/10.1186/1297-9716-44-59