Cargando…

Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) has a biased nucleotide composition different from human genes. This raises the question of how evolution has chosen the nucleotide sequence of HIV-1 that is observed today, or to what extent the actual encoding contributes to virus replication...

Descripción completa

Detalles Bibliográficos
Autores principales: Martrus, Gloria, Nevot, Maria, Andres, Cristina, Clotet, Bonaventura, Martinez, Miguel Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726367/
https://www.ncbi.nlm.nih.gov/pubmed/23885919
http://dx.doi.org/10.1186/1742-4690-10-78