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Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) has a biased nucleotide composition different from human genes. This raises the question of how evolution has chosen the nucleotide sequence of HIV-1 that is observed today, or to what extent the actual encoding contributes to virus replication...

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Detalles Bibliográficos
Autores principales:	Martrus, Gloria, Nevot, Maria, Andres, Cristina, Clotet, Bonaventura, Martinez, Miguel Angel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726367/ https://www.ncbi.nlm.nih.gov/pubmed/23885919 http://dx.doi.org/10.1186/1742-4690-10-78

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