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The promoter of miR-663 is hypermethylated in Chinese pediatric acute myeloid leukemia (AML)

BACKGROUND: There is growing evidence supporting a role for microRNAs (miRNA) as targets in aberrant mechanisms of DNA hypermethylation. Epigenetic silencing of tumor suppressor miRNAs, including miR-663, which has recently been reported to be inactivated by hypermethylation in several cancers, may...

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Detalles Bibliográficos
Autores principales: Yan-Fang, Tao, Jian, Ni, Jun, Lu, Na, Wang, Pei-Fang, Xiao, Wen-Li, Zhao, Dong, Wu, Li, Pang, Jian, Wang, Xing, Feng, Jian, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726388/
https://www.ncbi.nlm.nih.gov/pubmed/23870168
http://dx.doi.org/10.1186/1471-2350-14-74