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The promoter of miR-663 is hypermethylated in Chinese pediatric acute myeloid leukemia (AML)
BACKGROUND: There is growing evidence supporting a role for microRNAs (miRNA) as targets in aberrant mechanisms of DNA hypermethylation. Epigenetic silencing of tumor suppressor miRNAs, including miR-663, which has recently been reported to be inactivated by hypermethylation in several cancers, may...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726388/ https://www.ncbi.nlm.nih.gov/pubmed/23870168 http://dx.doi.org/10.1186/1471-2350-14-74 |