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Spatiotemporal Expression of Matrix Metalloproteinases (MMPs) is Regulated by the Ca(2+)-Signal Transducer S100A4 in the Pathogenesis of Thoracic Aortic Aneurysm
AIMS: This study investigated whether S100A4 plays a potential role in the formation of thoracic aortic aneurysm (TAA). METHODS AND RESULTS: The thoracic aortas of male Sprague-Dawley rats were exposed to 0.5 M CaCl2 or normal saline (NaCl). Animals were euthanized at specified time-points (2, 4, an...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726393/ https://www.ncbi.nlm.nih.gov/pubmed/23922901 http://dx.doi.org/10.1371/journal.pone.0070057 |