The Linker Pivot in Ci-VSP: The Key to Unlock Catalysis

In the voltage-sensitive phosphatase Ci-VSP, conformational changes in the transmembrane voltage sensor domain (VSD) are transduced to the intracellular catalytic domain (CD) leading to its dephosphorylation activity against membrane-embedded phosphoinositides. The linker between both domains is pro...

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Detalles Bibliográficos
Autores principales: Hobiger, Kirstin, Utesch, Tillmann, Mroginski, Maria Andrea, Seebohm, Guiscard, Friedrich, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726396/
https://www.ncbi.nlm.nih.gov/pubmed/23922964
http://dx.doi.org/10.1371/journal.pone.0070272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726396/
https://www.ncbi.nlm.nih.gov/pubmed/23922964
http://dx.doi.org/10.1371/journal.pone.0070272

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