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miR-99b-targeted mTOR induction contributes to irradiation resistance in pancreatic cancer

BACKGROUND: Radiation exerts direct antitumor effects and is widely used in clinics, but the efficacy is severely compromised by tumor resistance. Therefore uncovering the mechanism of radioresistance might promote the development of new strategies to overcome radioresistance by manipulating activit...

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Detalles Bibliográficos
Autores principales: Wei, Feng, Liu, Yan, Guo, Yanhai, Xiang, An, Wang, Guangyi, Xue, Xiaochang, Lu, Zifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726417/
https://www.ncbi.nlm.nih.gov/pubmed/23886294
http://dx.doi.org/10.1186/1476-4598-12-81