Cargando…

miR-99b-targeted mTOR induction contributes to irradiation resistance in pancreatic cancer

BACKGROUND: Radiation exerts direct antitumor effects and is widely used in clinics, but the efficacy is severely compromised by tumor resistance. Therefore uncovering the mechanism of radioresistance might promote the development of new strategies to overcome radioresistance by manipulating activit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Feng, Liu, Yan, Guo, Yanhai, Xiang, An, Wang, Guangyi, Xue, Xiaochang, Lu, Zifan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726417/ https://www.ncbi.nlm.nih.gov/pubmed/23886294 http://dx.doi.org/10.1186/1476-4598-12-81

Ejemplares similares

Co-targeting of IGF1R/mTOR pathway by miR-497 and miR-99a impairs hepatocellular carcinoma development
por: Cheng, Henghui, et al.
Publicado: (2017)

Insulin Promotes Glucose Consumption via Regulation of miR-99a/mTOR/PKM2 Pathway
por: Li, Wei, et al.
Publicado: (2013)

MiR-99a Antitumor Activity in Human Breast Cancer Cells through Targeting of mTOR Expression
por: Hu, Yu, et al.
Publicado: (2014)

Deregulation of miR-100, miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma
por: Torres, Anna, et al.
Publicado: (2012)

The role of the miR-99b-5p/mTOR signaling pathway in neuroregeneration in mice following spinal cord injury
por: Cao, Fujiang, et al.
Publicado: (2017)

miR-99a regulates CD4(+) T cell differentiation and attenuates experimental autoimmune encephalomyelitis by mTOR-mediated glycolysis
por: Gu, Yuting, et al.
Publicado: (2021)

Exosomal miR‐222‐3p contributes to castration‐resistant prostate cancer by activating mTOR signaling
por: Wang, Weixi, et al.
Publicado: (2023)

miR-99a-5p: A Potential New Therapy for Atherosclerosis by Targeting mTOR and Then Inhibiting NLRP3 Inflammasome Activation and Promoting Macrophage Autophagy
por: Wang, Gang, et al.
Publicado: (2022)

miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mTOR
por: Li, Wenhua, et al.
Publicado: (2015)

LncRNA‐DANCR contributes to lung adenocarcinoma progression by sponging miR‐496 to modulate mTOR expression
por: Lu, Qing‐chun, et al.
Publicado: (2017)

Targeting mTOR dependency in pancreatic cancer
por: Morran, Douglas C, et al.
Publicado: (2014)

Targeting mTOR in Pancreatic Ductal Adenocarcinoma
por: Iriana, Sentia, et al.
Publicado: (2016)

miR-7 Increases Cisplatin Sensitivity of Gastric Cancer Cells Through Suppressing mTOR
por: Xu, Ning, et al.
Publicado: (2017)

PTEN/AKT/mTOR pathway involvement in autophagy, mediated by miR-99a-3p and energy metabolism in ammonia-exposed chicken bursal lymphocytes
por: Ali Shah, Syed Waqas, et al.
Publicado: (2020)

Downregulation of miR-99b-5p and Upregulation of Nuclear mTOR Cooperatively Promotes the Tumor Aggressiveness and Drug Resistance in African American Prostate Cancer
por: Gujrati, Himali, et al.
Publicado: (2022)

Tumor suppressive miR-99b-5p as an epigenomic regulator mediating mTOR/AR/SMARCD1 signaling axis in aggressive prostate cancer
por: Waseem, Mohammad, et al.
Publicado: (2023)

mTOR Inhibition Induces EGFR Feedback Activation in Association with Its Resistance to Human Pancreatic Cancer
por: Wei, Feng, et al.
Publicado: (2015)

Everolimus and mTOR inhibition in pancreatic neuroendocrine tumors
por: Yim, Kein-Leong
Publicado: (2012)

FUS contributes to mTOR-dependent inhibition of translation
por: Sévigny, Myriam, et al.
Publicado: (2021)

Inflammatory-miR-301a circuitry drives mTOR and Stat3-dependent PSC activation in chronic pancreatitis and PanIN
por: Li, Fugui, et al.
Publicado: (2022)

miR-100 inhibits cell proliferation in mantle cell lymphoma by targeting mTOR
por: Lin, Luhui, et al.
Publicado: (2020)

miR-496, miR-1185, miR-654, miR-3183 and miR-495 are downregulated in colorectal cancer cells and have putative roles in the mTOR pathway
por: Alqurashi, Naif, et al.
Publicado: (2019)

miR-122 and miR-199 synergistically promote autophagy in oral lichen planus by targeting the Akt/mTOR pathway
por: Wang, Liang, et al.
Publicado: (2019)

MicroRNA-99 Family Targets AKT/mTOR Signaling Pathway in Dermal Wound Healing
por: Jin, Yi, et al.
Publicado: (2013)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

mTOR signaling contributes to motor skill learning in mice
por: Bergeron, Yan, et al.
Publicado: (2014)

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma
por: Minna, Emanuela, et al.
Publicado: (2016)

miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation
por: Li, Z, et al.
Publicado: (2017)

Bovine Pre-adipocyte Adipogenesis Is Regulated by bta-miR-150 Through mTOR Signaling
por: Chen, Xingyi, et al.
Publicado: (2021)

CircCASC15-miR-100-mTOR may influence the cervical cancer radioresistance
por: Yao, Tingting, et al.
Publicado: (2022)

miR-29c Increases Protein Synthesis in Skeletal Muscle Independently of AKT/mTOR
por: Alves, Paula Ketilly Nascimento, et al.
Publicado: (2022)

Myelination and mTOR
por: Figlia, Gianluca, et al.
Publicado: (2017)

miR-7 and miR-153 protect neurons against MPP(+)-induced cell death via upregulation of mTOR pathway
por: Fragkouli, Apostolia, et al.
Publicado: (2014)

miR-99a-5p acts as tumor suppressor via targeting to mTOR and enhances RAD001-induced apoptosis in human urinary bladder urothelial carcinoma cells
por: Tsai, Te-Fu, et al.
Publicado: (2018)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
por: Zou, Zhilin, et al.
Publicado: (2020)

JNK Contributes to the Tumorigenic Potential of Human Cholangiocarcinoma Cells through the mTOR Pathway Regulated GRP78 Induction
por: Feng, Chunhong, et al.
Publicado: (2014)

Suppression of mTOR pathway and induction of autophagy-dependent cell death by cabergoline
por: Lin, Shao Jian, et al.
Publicado: (2015)

IL‐38 prevents induction of trained immunity by inhibition of mTOR signaling
por: de Graaf, Dennis M., et al.
Publicado: (2021)

mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters
por: Liu, Yuanhui, et al.
Publicado: (2022)

mTOR Signaling Upregulates CDC6 via Suppressing miR-3178 and Promotes the Loading of DNA Replication Helicase
por: Wu, Xianjin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_k70ai65fq8g5p7sslkpsovm2q1