Efficient downregulation of VEGF in retinal pigment epithelial cells by integrin ligand-labeled liposome-mediated siRNA delivery

BACKGROUND: The purpose of this study was to demonstrate the effectiveness of an integrin peptide ligand-labeled liposomal delivery system loaded with vascular endothelial growth factor (VEGF)-siRNA in a model study of gene therapy for retinopathy using human retinal pigment epithelial cells. METHOD...

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Detalles Bibliográficos
Autores principales: Chen, Cheng-Wei, Yeh, Ming-Kung, Shiau, Chia-Yang, Chiang, Chiao-Hsi, Lu, Da-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726441/
https://www.ncbi.nlm.nih.gov/pubmed/23901275
http://dx.doi.org/10.2147/IJN.S39622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726441/
https://www.ncbi.nlm.nih.gov/pubmed/23901275
http://dx.doi.org/10.2147/IJN.S39622

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