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Designing a C(84) fullerene as a specific voltage-gated sodium channel blocker

Fullerene derivatives demonstrate considerable potential for numerous biological applications, such as the effective inhibition of HIV protease. Recently, they were identified for their ability to indiscriminately block biological ion channels. A fullerene derivative which specifically blocks a part...

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Detalles Bibliográficos
Autores principales: Hilder, Tamsyn A, Chung, Shin-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726465/
https://www.ncbi.nlm.nih.gov/pubmed/23855749
http://dx.doi.org/10.1186/1556-276X-8-323