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Folliculin Contributes to VHL Tumor Suppressing Activity in Renal Cancer through Regulation of Autophagy

Von Hippel-Lindau tumor suppressor (VHL) is lost in the majority of clear cell renal cell carcinomas (ccRCC). Folliculin (FLCN) is a tumor suppressor whose function is lost in Birt-Hogg-Dubé syndrome (BHD), a disorder characterized by renal cancer of multiple histological types including clear cell...

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Detalles Bibliográficos
Autores principales: Bastola, Prabhat, Stratton, Yiwen, Kellner, Emily, Mikhaylova, Olga, Yi, Ying, Sartor, Maureen A., Medvedovic, Mario, Biesiada, Jacek, Meller, Jarek, Czyzyk-Krzeska, Maria F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726479/
https://www.ncbi.nlm.nih.gov/pubmed/23922894
http://dx.doi.org/10.1371/journal.pone.0070030