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Folliculin Contributes to VHL Tumor Suppressing Activity in Renal Cancer through Regulation of Autophagy
Von Hippel-Lindau tumor suppressor (VHL) is lost in the majority of clear cell renal cell carcinomas (ccRCC). Folliculin (FLCN) is a tumor suppressor whose function is lost in Birt-Hogg-Dubé syndrome (BHD), a disorder characterized by renal cancer of multiple histological types including clear cell...
Autores principales: | Bastola, Prabhat, Stratton, Yiwen, Kellner, Emily, Mikhaylova, Olga, Yi, Ying, Sartor, Maureen A., Medvedovic, Mario, Biesiada, Jacek, Meller, Jarek, Czyzyk-Krzeska, Maria F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726479/ https://www.ncbi.nlm.nih.gov/pubmed/23922894 http://dx.doi.org/10.1371/journal.pone.0070030 |
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