Cisplatin and Doxorubicin Induce Distinct Mechanisms of Ovarian Follicle Loss; Imatinib Provides Selective Protection Only against Cisplatin

PURPOSE: Chemotherapy treatment in premenopausal women has been linked to ovarian follicle loss and premature ovarian failure; the exact mechanism by which this occurs is uncertain. Here, two commonly used chemotherapeutic agents (cisplatin and doxorubicin) were added to a mouse ovary culture system...

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Detalles Bibliográficos
Autores principales: Morgan, Stephanie, Lopes, Federica, Gourley, Charlie, Anderson, Richard A., Spears, Norah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726485/
https://www.ncbi.nlm.nih.gov/pubmed/23922929
http://dx.doi.org/10.1371/journal.pone.0070117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726485/
https://www.ncbi.nlm.nih.gov/pubmed/23922929
http://dx.doi.org/10.1371/journal.pone.0070117

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