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Recognition of Higher Order Patterns in Proteins: Immunologic Kernels

By applying analysis of the principal components of amino acid physical properties we predicted cathepsin cleavage sites, MHC binding affinity, and probability of B-cell epitope binding of peptides in tetanus toxin and in ten diverse additional proteins. Cross-correlation of these metrics, for pepti...

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Detalles Bibliográficos
Autores principales: Bremel, Robert D., Homan, E. Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726486/
https://www.ncbi.nlm.nih.gov/pubmed/23922927
http://dx.doi.org/10.1371/journal.pone.0070115