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In Vitro Efficient Transfection by CM(18)-Tat(11) Hybrid Peptide: A New Tool for Gene-Delivery Applications

Cell penetrating peptides (CPPs) are actively researched as non-viral molecular carriers for the controlled delivery of nucleic acids into cells, but widespread application is severely hampered by their trapping into endosomes. Here we show that the recently introduced endosomolytic CM(18)-Tat(11) h...

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Detalles Bibliográficos
Autores principales: Salomone, Fabrizio, Cardarelli, Francesco, Signore, Giovanni, Boccardi, Claudia, Beltram, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726494/
https://www.ncbi.nlm.nih.gov/pubmed/23922923
http://dx.doi.org/10.1371/journal.pone.0070108