The Innate Immunity Adaptor SARM Translocates to the Nucleus to Stabilize Lamins and Prevent DNA Fragmentation in Response to Pro-Apoptotic Signaling

Sterile alpha and armadillo-motif containing protein (SARM), a highly conserved and structurally unique member of the MyD88 family of Toll-like receptor adaptors, plays an important role in innate immunity signaling and apoptosis. Its exact mechanism of intracellular action remains unclear. Apoptosi...

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Detalles Bibliográficos
Autores principales: Sethman, Chad R., Hawiger, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726548/
https://www.ncbi.nlm.nih.gov/pubmed/23923041
http://dx.doi.org/10.1371/journal.pone.0070994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726548/
https://www.ncbi.nlm.nih.gov/pubmed/23923041
http://dx.doi.org/10.1371/journal.pone.0070994

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