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Epitope Mapping of Conformational V2-specific Anti-HIV Human Monoclonal Antibodies Reveals an Immunodominant Site in V2

In the case-control study of the RV144 vaccine trial, the levels of antibodies to the V1V2 region of the gp120 envelope glycoprotein were found to correlate inversely with risk of HIV infection. This recent demonstration of the potential role of V1V2 as a vaccine target has catapulted this region in...

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Detalles Bibliográficos
Autores principales: Mayr, Luzia M., Cohen, Sandra, Spurrier, Brett, Kong, Xiang-Peng, Zolla-Pazner, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726596/
https://www.ncbi.nlm.nih.gov/pubmed/23923028
http://dx.doi.org/10.1371/journal.pone.0070859