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A Metabolically-Stabilized Phosphonate Analog of Lysophosphatidic Acid Attenuates Collagen-Induced Arthritis

Rheumatoid arthritis (RA) is a destructive arthropathy with systemic manifestations, characterized by chronic synovial inflammation. Under the influence of the pro-inflammatory milieu synovial fibroblasts (SFs), the main effector cells in disease pathogenesis become activated and hyperplastic while...

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Detalles Bibliográficos
Autores principales: Nikitopoulou, Ioanna, Kaffe, Eleanna, Sevastou, Ioanna, Sirioti, Ivi, Samiotaki, Martina, Madan, Damian, Prestwich, Glenn D., Aidinis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726599/
https://www.ncbi.nlm.nih.gov/pubmed/23923032
http://dx.doi.org/10.1371/journal.pone.0070941