Abundant Intracellular IgG in Enterocytes and Endoderm Lacking FcRn

FcRn, a non-classical MHCI molecule, transports IgG from mother to young and regulates the rate of IgG degradation throughout life. Brambell proposed a mechanism that unified these two functions, saying that IgG was pinocytosed nonspecifically by the cell into an FcRn-expressing endosome, where, at...

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Detalles Bibliográficos
Autores principales: Mohanty, Sudhasri, Kim, Jonghan, Ganesan, Latha P., Phillips, Gary S., Robinson, John M., Anderson, Clark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726603/
https://www.ncbi.nlm.nih.gov/pubmed/23923029
http://dx.doi.org/10.1371/journal.pone.0070863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726603/
https://www.ncbi.nlm.nih.gov/pubmed/23923029
http://dx.doi.org/10.1371/journal.pone.0070863

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