ß-Blocker Timolol Prevents Arrhythmogenic Ca(2+) Release and Normalizes Ca(2+) and Zn(2+) Dyshomeostasis in Hyperglycemic Rat Heart

Defective cardiac mechanical activity in diabetes results from alterations in intracellular Ca(2+) handling, in part, due to increased oxidative stress. Beta-blockers demonstrate marked beneficial effects in heart dysfunction with scavenging free radicals and/or acting as an antioxidant. The aim of...

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Detalles Bibliográficos
Autores principales: Tuncay, Erkan, Okatan, Esma N., Vassort, Guy, Turan, Belma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726605/
https://www.ncbi.nlm.nih.gov/pubmed/23923043
http://dx.doi.org/10.1371/journal.pone.0071014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726605/
https://www.ncbi.nlm.nih.gov/pubmed/23923043
http://dx.doi.org/10.1371/journal.pone.0071014

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