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ß-Blocker Timolol Prevents Arrhythmogenic Ca(2+) Release and Normalizes Ca(2+) and Zn(2+) Dyshomeostasis in Hyperglycemic Rat Heart
Defective cardiac mechanical activity in diabetes results from alterations in intracellular Ca(2+) handling, in part, due to increased oxidative stress. Beta-blockers demonstrate marked beneficial effects in heart dysfunction with scavenging free radicals and/or acting as an antioxidant. The aim of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726605/ https://www.ncbi.nlm.nih.gov/pubmed/23923043 http://dx.doi.org/10.1371/journal.pone.0071014 |