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Amiodarone Inhibits Apamin-Sensitive Potassium Currents

BACKGROUND: Apamin sensitive potassium current (I (KAS)), carried by the type 2 small conductance Ca(2+)-activated potassium (SK2) channels, plays an important role in post-shock action potential duration (APD) shortening and recurrent spontaneous ventricular fibrillation (VF) in failing ventricles....

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Detalles Bibliográficos
Autores principales: Turker, Isik, Yu, Chih-Chieh, Chang, Po-Cheng, Chen, Zhenhui, Sohma, Yoshiro, Lin, Shien-Fong, Chen, Peng-Sheng, Ai, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726612/
https://www.ncbi.nlm.nih.gov/pubmed/23922993
http://dx.doi.org/10.1371/journal.pone.0070450