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Altered Islet Morphology but Normal Islet Secretory Function In Vitro in a Mouse Model with Microvascular Alterations in the Pancreas

BACKGROUND: Our previous studies have shown that signal transducer and activator of transcription 3 (STAT3) signaling is important for the development of pancreatic microvasculature via its regulation of vascular endothelial growth factor-A (VEGF-A). Pancreas-specific STAT3-KO mice exhibit glucose i...

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Detalles Bibliográficos
Autores principales: Kostromina, Elena, Wang, Xiaorui, Han, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726616/
https://www.ncbi.nlm.nih.gov/pubmed/23923060
http://dx.doi.org/10.1371/journal.pone.0071277